Xinhua News Agency, Beijing, May 16th Title: Out-and-out false proposition and political manipulation full of lies — — Authoritative experts comment on people with ulterior motives and speculate that "Taiwan Province participates in the World Health Assembly"

　　Xinhua News Agency reporter Shi Longhong Li Hanfang

　　The 73rd World Health Assembly will be held from May 18th to 19th. At this time, the Democratic Progressive Party authorities stepped up the pace of "seeking independence through the epidemic", linked with the United States and other individual countries, and hyped up the so-called "Taiwan Province’s participation in the World Health Assembly". A number of authoritative experts told Xinhua that the so-called "Taiwan Province’s participation in the World Health Assembly" is a completely false proposition. The Democratic Progressive Party authorities are not really concerned about public health issues, but politicize the issue of epidemic prevention for the self-interest of political parties. The mainland has always attached great importance to the health and well-being of Taiwan Province compatriots, and continued to provide assistance for Taiwan Province to obtain public health information in a timely manner. According to the arrangement reached between China and WHO, on the basis of the one-China principle, Taiwan Province has smooth access to relevant information released by WHO, and Taiwan Province medical and health experts continue to participate in WHO technical activities in their personal capacity. Attempts by people with ulterior motives to kidnap the World Health Assembly by political manipulation full of lies will interfere with the process of the Assembly, undermine global cooperation in the fight against epidemic diseases, and do no good to the health of Taiwan Province people. On the contrary, it will worsen cross-strait relations, which will surely be resolutely opposed by compatriots on both sides of the strait and the international community.

　　Taiwan Province’s participation in the activities of international organizations must be handled according to the one-China principle. The failure to attend the World Health Assembly was caused by the Democratic Progressive Party authorities.

　　Yan Anlin, vice president of Shanghai Institute of International Studies, said that there is only one China in the world and Taiwan Province is a part of China. Taiwan Province’s participation in the activities of international organizations, including WHO, must be handled according to the one-China principle. The United Nations has repeatedly reiterated that it will adhere to the UN General Assembly Resolution 2758 to deal with the Taiwan Province issue. As a specialized agency of the United Nations composed of sovereign States, WHO abides by the resolutions of the General Assembly, and resolution 25.1 of the World Health Assembly reaffirmed resolution 2758 of the General Assembly. These are all hard facts, and there is no doubt about it.

　　He pointed out that the Constitution of the World Health Organization and the Rules of Procedure of the World Health Assembly clearly stipulate that only sovereign countries are eligible to become members or associate members of WHO, and only sovereign countries, overseas territories or relevant international organizations that have not formally joined WHO are eligible to be invited to attend the WHO as observers. As a part of China, Taiwan Province is not eligible to attend the World Health Assembly as an observer. The World Health Assembly has rejected Taiwan-related proposals submitted by a few countries for many years, which fully reflects the general consensus of the international community in adhering to the one-China principle.

　　From 2009 to 2016, Taiwan Province participated in the World Health Assembly in the name of "Chinese Taipei" and as an observer for eight consecutive years. Deputy Secretary-General of the National Taiwan Province Research Association said sternly that this was a special arrangement made through cross-strait negotiations on the basis of the "1992 Consensus" that both sides of the strait adhered to the one-China principle. However, after Democratic Progressive Party took office, he put political schemes above the well-being of Taiwan Province compatriots, stubbornly adhered to the "Taiwan independence" separatist stance and refused to recognize the "1992 Consensus", which led to the disappearance of the political foundation for Taiwan Province’s participation in the World Health Assembly, and the relevant arrangements were naturally unsustainable. Taiwan Province’s inability to participate in the World Health Assembly was caused by the Democratic Progressive Party authorities, and the Democratic Progressive Party authorities are well aware of it.

　　Wang Yingjin, director of the Research Center for Cross-Strait Relations of Renmin University of China, analyzed that Taiwan Province is not a sovereign country, so it is certainly ineligible to join international intergovernmental organizations composed of sovereign countries. Only on the common political basis of adhering to the "1992 Consensus" and opposing the "Taiwan independence" can the two sides make relevant special arrangements through pragmatic consultation and proper arrangements. The Democratic Progressive Party authorities are stubborn, trying to achieve a "breakthrough" with the support of some countries, such as the United States, while making "Taiwan independence" moves. This year, they are even more arrogant and have provoked some countries to put forward Taiwan-related proposals, even at the expense of kidnapping the World Health Assembly and damaging global cooperation against the epidemic to seek their own political interests. The consequences of the above-mentioned practices will seriously interfere with the process of the General Assembly and undermine international cooperation in fighting the epidemic, and will be resolutely opposed by the overwhelming majority of members of the international community, which is impossible to succeed.

　　The mainland really cares about the health and well-being of Taiwan compatriots. The information channels between Taiwan Province and WHO are smooth and technical cooperation is unimpeded.

　　Since the outbreak, the Democratic Progressive Party authorities have repeatedly speculated on the WHO’s involvement in Taiwan, fabricated and spread rumors, falsely accused the mainland of concealing the epidemic situation in Taiwan, and claimed that Taiwan Province’s absence from WHO and the World Health Assembly would create an "international epidemic prevention gap" and threaten the health of Taiwan Province people. After being refuted by WHO, they made vicious attacks on WHO and its responsible persons and made unreasonable demands that violated the relevant provisions of international organizations. In this regard, experts pointed out that the Democratic Progressive Party authorities are full of lies, black and white are reversed, and politicians and media in individual countries are following suit and spreading false information with ulterior motives.

　　Yan Anlin said that the mainland has always attached great importance to the health and well-being of Taiwan compatriots and made proper arrangements for Taiwan Province to participate in global health affairs under the premise of the one-China principle. According to the arrangement reached between China and WHO, health institutions in Taiwan Province can obtain information released by WHO in time and update information directly to WHO through the contact window under the framework of WHO’s International Health Regulations. Medical and health experts in Taiwan Province have been attending relevant WHO meetings in appropriate capacity. These arrangements ensure that Taiwan Province can respond to public health emergencies in a timely and effective manner, whether on the island or internationally.

　　The data shows that from the beginning of 2019 to the beginning of May 2020, 16 groups of 24 experts from Taiwan Province participated in WHO technical activities. On January 3rd, the mainland started the emergency notification mechanism for cross-strait public health emergencies, and informed Taiwan’s disease control departments of the epidemic situation in time. On January 12th, it specifically informed relevant parties in Taiwan about the sharing of Covid-19’s gene sequence with WHO and the ways to obtain related gene sequences. From January 12th to 14th, Taiwan Province experts were specially arranged to make a field trip to Wuhan to learn about the diagnosis, treatment and epidemic situation of patients diagnosed in COVID-19. It is understood that from February 5 to March 8, the mainland has shared 26 key technical materials with Taiwan; As of May 15th, the mainland has informed Taiwan of the epidemic situation 152 times.

　　"The mainland has always maintained communication with relevant parties in Taiwan Province in the spirit of attaching great importance to the health and well-being of compatriots on both sides of the strait, and the channels for to obtain public health information released by WHO are also smooth. The Democratic Progressive Party authorities call it ‘ International epidemic prevention gap ’ And threats to the health of Taiwan Province people are completely untenable. " Wang Yingjin said, on the other hand, Democratic Progressive Party authorities’ treatment of Taiwan compatriots stranded in Hubei shows that they are not really concerned about people’s lives and health, only thinking about political abacus and taking the opportunity to seek "independence", taking people’s interests as political chips and showing the greatest disrespect to the people.

　　Seriously, the Democratic Progressive Party authorities hyped the issue of participating in the World Health Assembly, not to obtain technical parameters, not to safeguard the health rights and interests of Taiwan Province people, but to flaunt the existence of so-called "sovereignty". Its claim that "not allowing Taiwan Province to participate in the World Health Assembly will lead to a gap in the international epidemic prevention system" does not exist at all, but is a lie and an excuse. The Democratic Progressive Party authorities’ hype about this issue at this time is to "seek independence through the epidemic", which is an out-and-out political manipulation, and it is not only unhelpful but also harmful to the well-being of the people of Taiwan Province.

　　Using the epidemic to speculate on WHO’s Taiwan-related issues is entirely out of political conspiracy, wrong and dangerous actions, which further push Taiwan Province to danger.

　　Seriously, it is pointed out that the United States has recently openly pleaded for Taiwan Province’s participation in the World Health Assembly and made great efforts to "perform", with obvious intentions. American politicians don’t care about the health and well-being of Taiwan Province people. There are two purposes behind manipulating Taiwan Province to join WHO and attend the World Health Assembly. First, to enhance the so-called "US-Taiwan relationship", make Taiwan Province more closely attached to the United States, and strengthen the strategic influence of the United States in East Asia; The second is an attempt to put pressure on the China administration to cater to the needs of the "pro-Taiwan" right-wing forces in the United States. Under the current background of Sino-US relations, the United States, which is used to playing the "Taiwan Province card", has made a fuss about the World Health Assembly in order to make better use of Taiwan Province to contain Chinese mainland.

　　"The Democratic Progressive Party authorities tried to link up the support of some western countries and politicians, highlighting Taiwan Province’s so-called ‘ International presence ’ 。” Wang Yingjin said that what Democratic Progressive Party authorities really care about is not the outcome of Taiwan Province’s participation in the World Health Assembly. If it fails, it will just continue to "throw the pot" on the mainland and attack the mainland for ignoring the life and health rights of Taiwan Province people, so as to further incite the "anti-China hatred against China" populism on the island, raise cross-strait confrontation and achieve the political goals of "de-China" and various forms of "Taiwan independence".

　　Li Peng, dean of Taiwan Province Research Institute of Xiamen University, believes that Democratic Progressive Party authorities believe that the epidemic provides an opportunity for them to promote the "Taiwan independence" process, and attempt to take the opportunity to strengthen the "independence" consciousness of Taiwan Province people, highlight Taiwan Province’s status as an "independent country" in the international community, and seek to promote "legal Taiwan independence". This attempt to incite populism to cover up the fact of its incompetence in administration and to provoke cross-strait confrontation to escort its "Taiwan independence" action is tantamount to taking the interests and well-being of the 23 million Taiwan Province compatriots as their own political bet.

　　He said that in order to give courage to "seek independence through the epidemic", the Democratic Progressive Party authorities colluded with the anti-China forces in the United States and fully catered to the political operation of the United States to "throw the pot" at China. The Democratic Progressive Party authorities think that the complicated situation of Sino-US relations is a "good opportunity" for them to seek external support from the "de jure Taiwan independence", but in fact they have miscalculated. Willing to be a "pawn" of the United States at this time will push Taiwan Province to a more dangerous situation, and the United States cannot provide substantial help to the Democratic Progressive Party authorities in expanding the so-called "international space." The vast number of Taiwan Province compatriots should keep their eyes open and see who is really working for the well-being of Taiwan Province compatriots and who has repeatedly used the interests of Taiwan compatriots as a bargaining chip for personal gain.

Image source: Xinmin. com

CCTV News:There are more than 2,000 parts and components in a car. Miao Liqi remembers them all, and she can’t accept them! It takes only 7 hours to complete the assembly of a whole vehicle independently? This is a piece of cake for Miao Liqi.

Miao Liqi is the section chief of the assembly workshop of Shanghai GM-Wuling Qingdao Branch, as well as the "Qingdao Chief Technician" and the "national operation technical expert". "I can assemble a car independently offline without the help of a workshop assembly line, and the whole process only takes 7 hours." This is not bragging. Miao Liqi now has a number of intermediate and senior skill level certificates, including welders, fitters, maintenance workers and engine assemblers, and he is also proficient in all major events and small situations in the workshop. Only 30 years old this year, how did he practice this "god skill"?

Interest is the best teacher.

Miao Liqi was born in a rural family in Gongzhuling, Jilin Province. He was very interested in the disassembly and maintenance of agricultural vehicles since he was a child. Later, he studied mechanical and electrical engineering at China Jiaotong University, and worked in an automobile company after graduation. It can be said that his long-cherished wish has been realized.

"I’ll show you again. Whether you can learn it depends on your understanding!" In June 2005, the company’s assembly workshop was an ordinary mentoring exercise, from which Miao Liqi entered the business. After 11 years of polishing, "auto parts worker" Miao Liqi has now grown into an "all-rounder of auto parts".

At a glance, you can judge which screw of the automobile interior is not screwed in place; You can judge which part of the engine is caused by listening with your ears. With diligent exploration spirit and hard-working style, Miao Liqi has developed a set of excellent automobile professional technology and solid business ability.

Thanks to "obsessive-compulsive disorder": it must be 100%

"The car that has passed my hand must be striving for perfection, and it cannot have the slightest defect. It can reach 100% and never 99%."

Always want to do things to the extreme, always feel that knowledge is not enough, which is the perfectionism of Miao Liqi, a "master of technology", and also his obsessive-compulsive disorder. It is not only the mapping of the craftsman spirit in the new era, but also the consistent pursuit of Miao Liqi.

Although he has already grown into a well-known craftsman and technician in the company, Miao Liqi feels that now is the golden age of life learning and accumulation. He used his spare time to catch up with his professional knowledge, learn management knowledge, take exams to improve his academic qualifications, and even recited the learning content in his dreams. Although he has grown from an ordinary assembly worker to a site manager in just three years, he said that he will continue to improve his professional knowledge and skill level with the mentality of "eager to learn, humble and foolish", and at the same time try to develop horizontally to make himself more professional and comprehensive in the field of vehicle assembly.

Masters love "invention": there is no end to innovation

Miao Liqi’s various suggestions on technological innovation are too numerous to mention, among which four have obtained company patents.

Colleagues really admire Miao Liqi. In addition to his technical proficiency, his innovation and creation also liberated everyone’s arms. Before installing a spare tire, it was necessary to put the arm under the chassis and rely on the strength of the arm to lift it. At the end of the day, almost everyone’s arm would be weak and weak. This problem inspired Miao Liqi to be willing to learn, and he just invented a spare tire machine. He uses the principle that the cylinder can be lifted by the control valve to make a car. After pressing the control valve, the spare tire can be installed on the car by lifting the cylinder, and the work efficiency is more than doubled.

Began in the way, the craftsman is in the heart. Miao Liqi’s life in Dont Ask For Help is brilliant. I only hope that every process I handle will be meticulously crafted and refined, and everything will be done in a down-to-earth manner. (Source of material clues: Zhonggong. com)

The Henan Meteorological Observatory upgraded to issue a yellow rainstorm warning at 8: 00 on July 3, 2023: It is estimated that there will be heavy rain (50-80 mm) in some counties and cities in northern and eastern Nanyang, southern Pingdingshan, eastern Luohe, Zhumadian, northwest Xinyang, Zhoukou and eastern Shangqiu from 8: 00 on July 3 to 8: 00 on July 4, among which the rainfall at individual stations in northern and eastern Nanyang, southwest Pingdingshan and eastern Zhoukou can reach more than 100 mm, accompanied by lightning and lightning. Please take precautions. Neighboring counties and cities (districts) in the above areas also need attention.

Defense guide:

1. The government and relevant departments shall, in accordance with their duties, do a good job in preparing for rainstorm prevention, and pay close attention to the latest forecast information and meteorological disaster warning signals issued by the local meteorological departments;

2. Schools and kindergartens can advance or postpone school hours to ensure the safety of students and children.

3. When driving, make sure that the brakes, steering, wipers and other components are safe and effective. When encountering a section with deep water, don’t wade through it rashly. When the vehicle turns off during wading, evacuate quickly before the water level rises, and don’t wait for rescue in the car.

4. Pedestrians should stay away from temporary fences on construction sites and fences built on hillsides, be alert to manhole covers, sewers and sewage wells, avoid hanging wires, avoid touching lamp post or signal lamp poles, avoid electric leakage, and avoid rain under trees.

5. Check the drainage system of cities, farmland and fish ponds, and take drainage measures.

On July 2nd, Nanyang issued an early warning and forecast of geological disasters in flood season. The details are as follows:

Early warning and prediction of geological disasters in flood season in Nanyang city

Early warning and forecasting period: 20: 00 on July 2, 2023 ~ 20: 00 on July 3, 2023.

According to the Meteorological Risk Early Warning of Geological Disasters jointly issued by Henan Provincial Department of Natural Resources and Henan Meteorological Bureau on July 2, Nanyang Natural Resources and Planning Bureau, together with Nanyang Meteorological Bureau and Henan First Geological Exploration Institute Co., Ltd., the technical support unit, compiled the early warning and forecast of geological disasters in flood season in our city, as follows:

First, the meteorological risk early warning of regional geological disasters

From 20: 00 on July 2 to 20: 00 on July 3, 2023:

Areas with yellow warning of geological disasters: Xichuan County, Xixia County, nanzhao county, neixiang county, zhenping county and Fangcheng County.

Two, the county (township) meteorological risk warning of geological disasters

The yellow warning area of geological disasters:

Xichuan County: Jingziguan Town, Xihuang Township, Maotang Township, Shangji Town, Taohe Township, Shengwan Town, Cangfang Town, Madeng Town, Xianghua Town, Houpo Town and Jiucheng Town;

Xixia County: Sangping Town, Shijiehe Town, Miping Town, Junmahe Town, Taiping Town, Erlangping Town, Zhaigen Township, Dinghe Town, Shuanglong Town, xiping town, Chongyang Town, Wuliqiao Town, Huicheng Town and Yangcheng Town;

Nanzhao county: Qiaoduan Town, ban shan ping, Suburban Township, Liushan Town, Nanhedian Town, Sikeshu Township, Shimen Township, Taishanmiao Township, Huangludian Town, Xiaodian Township, Yunyang Town and Queens Township;

Neixiang county: Xiaguan Town, Banchang Township, Qiliping Township and Wating Town;

Zhenping county: Erlong Township, Wanggang Township, Shifosi Town, Laozhuang Town, Liu Quan Puzhen Town, Zheshan Town and Pengying Town;

Fangcheng County: Silidian Town, Guaihe Town, liuhe town, Qinghe Town, Yangji Town, Dushu Town, Guangyang Town and Yuandian Hui Township.

Geological disasters such as collapse and landslide are more likely to occur in the above areas.

Third, preventive measures:

1, pay close attention to the rain information, cooperate with the meteorological department to dynamically judge the risk of geological disasters, and send early warning information to villages, households and people in time.

2, strengthen the inspection of geological hazards.

3, all responsible units should increase the hidden danger point outside the hillside, ditch village, slope building, traffic trunk lines, important pipelines, tourist attractions, schools and other key parts of the investigation and inspection. In case of emergency, take immediate measures such as closure and evacuation.

4. Strengthen the duty on duty and prepare for the emergency response of sudden geological disasters. Once the disasters and dangers of geological disasters are discovered, the emergency response will be started immediately, and the disasters and dangers will be handled well.

5. The local government should make scientific analysis and in-depth judgment, and once a dangerous situation or disaster is found, resolutely achieve "three evacuations and one resettlement".

July 2, 2023

Affected by rainfall

The highest temperature in the province today and tomorrow

It drops slightly from north to south.

But in the next few days,

The high temperature will "make a comeback"

Especially in the northern and central regions.

The highest temperature is above 35 degrees from 5 to 8 days.

Some counties and cities can reach 39 to 41 degrees.

Beware of heatstroke

Provincial weather forecast

Today, the whole province is cloudy, with moderate to heavy rain in most parts of the north of Huaihe River, heavy rain in some counties and cities in the central, eastern and southwestern parts, and heavy rain in some parts, accompanied by strong convective weather such as short-term heavy precipitation; There are showers and thunderstorms in other counties and cities.

On the 4 th, showers and thunderstorms in the southeast and east stopped turning cloudy; Cloudy to sunny days in other counties and cities.

On the 5th, the whole province was cloudy on sunny days.

On the 6 th to 7 th, the southeast was cloudy and cloudy, with showers and thunderstorms; Other counties and cities are cloudy on sunny days.

On the 8 th, the south was cloudy; Other counties and cities are sunny to cloudy.

From May 5 to 8, the highest temperature in the north and central part is above 35 degrees, and some counties and cities can reach 39 to 41 degrees.

The meteorological department reminded:

1. The public should pay close attention to the latest forecast information and meteorological disaster warning signals issued by the local meteorological department.

2. During precipitation, it is necessary to guard against the adverse effects of slippery roads and low visibility weather on transportation and public travel.

Railway construction planning

Source/Nanyang Net Comprehensive Henan Meteorology and Nanyang New Meteorology

Original title: "Just now! Nanyang rainstorm warning upgrade! 》

Read the original text

CCTV News:According to the website of the Central Meteorological Observatory, the red warning signal of Blizzard was released by the Inner Mongolia Autonomous Region Meteorological Observatory at 07: 30 on November 6, 2023: within 6 hours, the snowfall will reach more than 15 mm in some areas in the east-southeast of Chifeng City, southwest of Tongliao City and west of central China, which may have a great impact on traffic or agriculture and animal husbandry. Please prepare for the relevant units and personnel.

Defense guide:

1. The government and relevant departments shall, in accordance with their duties, do a good job in emergency and rescue work against snow disaster and freezing injury;

2. If necessary, suspend classes or business (except for special industries);

3. When necessary, the aircraft will be suspended from taking off and landing, the train will be suspended, and the expressway will be temporarily closed;

4. Do a good job in disaster relief work in pastoral areas.

In addition, the Meteorological Observatory of Inner Mongolia Autonomous Region issued a yellow warning signal for road icing at 07: 11 on November 6, 2023: due to the impact of snowfall, it is expected that there may be road icing in the southeast of Alashan League, the east of Bayannaoer City, most of Baotou City, the north of Hohhot City, Wulanchabu City, most of Xilin Gol League, Chifeng City, Tongliao City and most of Xing ‘an League in the next 12 hours. Please prepare for the relevant units and personnel.

Defense guide:

1. Traffic, public security and other departments should prepare for road icing according to their duties;

2. Drivers should pay attention to road conditions and drive safely;

3. Pedestrians should ride bicycles as little as possible when going out, and pay attention to anti-skid.

　　Soda music will also display the ip address. As long as the user authorizes the software to obtain the user’s geographical location information, the detailed ip address will be displayed. So how to set the location of soda music? Let Xiaobian give you a detailed introduction.

　　How to set the location of soda music

　　Open my page and click the "Settings" icon.

　　Click the "personal data modification" option.

　　Click the "Location" setting item.

　　Click the "Click to open positioning" icon.

　　Click the "Allow only during use" button to open app positioning.

Comparative literature in three key words

Time:June 25th (Friday) 19:00-21:00.

Location:Tencent conference (ID: 850267852)

Speaker:Zhang Hui (Professor and Doctoral Supervisor, Chinese Department, Peking University)

Taking examples as the guide, this lecture reviews the definitions of comparative literature by Bosnett, Brunel and remarque, and analyzes the uncertainty and interdisciplinary characteristics of this subject. Furthermore, starting from some basic consensus that comparative scholars have formed, this paper deepens and extends the new understanding of "what is comparative literature" around three key words: "leap", "plural" and "the other". At the same time, with the help of the perspectives of Levinas, Muzil and others, the philosophical thinking on comparative problems is further triggered.

The story of a blind girl and a small town in Malay —— A new book sharing meeting of Li Zishu’s Land of Vulgarity

Time:19:00 on June 26th (Saturday)

Location:Hey, Beijing News APP, Weibo, Aauto Quicker, Tik Tok, etc.

Guest:Wang Anyi (writer), Chen Sihe (senior professor of liberal arts and doctoral supervisor of Fudan University), Zhai Yejun (professor of Chinese Department of Zhejiang University) and Li Zishu (writer).

In recent years, Malaysian Chinese literature (referred to as "Malaysian Chinese literature") has gradually entered our field of vision. Li Zishu, the protagonist of this activity and the author of "Vulgar Land", turned the big problem into an obscure obsession from the trivial daily life of dressing and eating through grotesque, delicate and realistic stories from her female perspective. On June 26th, Chen Sihe, a professor at Fudan University, Zhai Yejun, a professor at Zhejiang University, and Li Zishu, a Malaysian writer and author of "Land of Vulgarity", were invited by the Beijing News Book Review Weekly and Cultural Living Room in conjunction with Beijing October Literature and Art Publishing House to talk about Malaysian literature and a story about a blind girl and a small Malay town …

Breakthrough: Recitation and Dialogue Scene 4-International Poetry Nights in Hong Kong Series

Time:20:00 on June 26th (Saturday)

Location:Phoenix net

Guest:Gao Qiao Mu Lang (poet) and Tian Yuan (poet)

Gao Qiao Mulang, born on December 15th, 1937, is one of the most outstanding and prolific male poets, essayists and writers in contemporary Japan. He has more than 30 books of poetry, several prose works, dozens of prose monographs and several important literary awards. In the fourth scene of International Poetry Nights in Hong Kong series, we invited Gao Qiao Mulang to talk with China poet Tian Yuan, and invited musician Zhong Lifeng as the guest performer.

Conceiving and standardizing time: a cross-cultural historical discussion

Time:19:00 on Tuesday, June 29th.

Location:Tencent conference (ID: 203705266, password: 112233)

Guest:Guo Jinsong (postdoctoral fellow, Department of History, Peking University), Li Fupeng (Associate Professor, School of Law, China University of Political Science and Law), Liu Jinyu (Professor, Department of World History, Shanghai Normal University, Professor, Department of Classics, Depot University, USA), Wang Xianhua (Professor, Doctoral Supervisor, Shanghai International Studies University), Wang Yuanchong (Associate Professor, Department of History, University of Delaware, USA), etc.

What are the ways and paths to regulate time in history? Is there any essential difference between the time under the framework of empire and the time of polis? What historical enlightenment can we get from comparing the societies in different time frames? How do the ways of constructing and regulating time between different cultures influence each other? Is there any difference or change in individual’s cognition of time due to different social, economic and political status? This round-table forum adopts the perspective of seeing the big from the small, and takes dialogue as the main form, expecting the knowledge collision between researchers from two river basins, ancient Egypt, ancient India, Judaism, ancient Greece and Rome, the Middle Ages, China and other different cultures or different historical periods.

Attachment: Preview of offline activities

Beijing | How Far Is It? —— A New Book Sharing Meeting of Countless Plum Blossoms Falling on the Wild Bridge

Time:June 26th (Saturday) 15:00-17:00.

Location:SKP RENDEZ-VOUS, 4th floor, Beijing SKP Shopping Center, No.87 Jianguo Road, Chaoyang District

Guest:Qiao Ye (writer), Zhou Xiaofeng (writer), Liang Hong (scholar, writer, professor of China Renmin University) and Yan Hui (deputy editor-in-chief of Writers Publishing House).

Countless Plum Blossoms Falling on the Wild Bridge is the first collection of beautiful travel essays by Qiao Ye, a famous writer, and many of them have been selected for senior high school Chinese reading analysis and senior high school Chinese examination papers. How far is it? It can be in the sky or in front of you. Fortunately, in the days when the mind can’t soar, there are still good books that can put wings on us. Let travel become a habit, and let all journeys be accompanied by beautiful scenery. On June 26th, we invited writer Zhou Xiaofeng, scholar and writer Liang Hong, Yan Hui, deputy editor-in-chief of Writers Publishing House, and Qiao Ye, the author of "Numerous Plum Blossoms Fall on the Wild Bridge", to visit SKP in Beijing to talk about the distant and immediate scenery.

Beijing | When you come to the world, you should see what it looks like —— A new book sharing session of "Chasing the Hidden"

Time:June 26th (Saturday) 19:00-21:00

Location:SKP RENDEZ-VOUS, Floor 2, Beijing SKP-S Shopping Center, No.86 Jianguo Road, Chaoyang District

Guest:Liang Zi (photographer), Han Fei (former travel channel producer), Yu Su (media person)

In 2021, when the epidemic is still raging, have you been away for a long time to see what the world looks like? On June 26th, we invited Liang Zi, the author of Africa Decade, a photographer, Han Fei, a former travel channel producer, and Yu Su, a professional media person and the author of Chasing the Hidden Story, to visit SKP-S and talk about the distant place where our hearts are.

Beijing | hitting the water in the middle stream —— Young Mao Zedong’s reading thinking and life world

Time:June 27th (Sunday) 19:00-21:00.

Location:Room 441, Mengminwei Humanities Building, Tsinghua University, No.30 Shuangqing Road, Haidian District

Guest:Yuan Xianxin (Associate Professor of Chinese Department of Tsinghua University College of Humanities), Li Yurong (Ph.D. student of Peking University Department of History), Dong Yanyan (Ph.D. student of political science of Tsinghua University College of Social Sciences), etc.

In the early 20th century, China forged its youth era in the drastic social transformation. As a cultural symbol, "youth" not only symbolizes the most dynamic ideological form in the new world, but also reflects the national mentality of seeking change and striving for survival; At the same time, it is a thorough revaluation of all cultural values. The discussion in this salon focuses on the graduate students who are both in their youth. In the resonance of historical feelings, we will try to understand and think about the ideological change and revolutionary motivation of young Mao Zedong in combination with specific regional culture and characteristics of the times, so as to add a vivid and profound thinking material for us to understand the internal logic of modern history of China.

Beijing | A good story is a gift of life.

Time:June 27th (Sunday) 19:00-21:00.

Location:SKP RENDEZ-VOUS, 4th floor, Beijing SKP Shopping Center, No.87 Jianguo Road, Chaoyang District

Guest:Jing Li (deputy editor-in-chief of Sanlian Life Weekly) and Zhou Yijun (reporter and director)

On June 27th, Li Jing, deputy editor-in-chief of Sanlian Life Weekly, with a good story, and Zhou Yijun, a famous journalist and director, were in SKP, Beijing, to talk with you about books and hearts. Of course, in addition to the stories in the book, you also have the opportunity to hear the stories of the two guests themselves-about career, about family, about walking and about life. What is an excellent modern independent female benchmark? Maybe they are the answer.

Shanghai | Literature and News

Time:June 25th (Friday) from 14: 00 to 16: 00.

Location:The first meeting room on the 20th floor of The Paper, No.839 Yan ‘an Middle Road, Jing ‘an District.

Speaker:Shen Weirong (Professor and Doctoral Supervisor, Chinese Department, Tsinghua University)

In the afternoon tea, Professor Shen Weirong from Tsinghua University was invited to give a lecture on Chinese literature and news.

Shanghai | Under the cloak of night, the story sails to an unknown place —— Sharing meeting of Bola? o’s collection of short stories "Return to the Night"

Time:June 25th (Friday) 19:00-21:00.

Location:3/F, No.150 Pucheng Road, Pudong New Area, Shanghai Pudong Library Rong Study Room

Guest:Zhao Song (writer), btr (writer, translator, cultural critic)

In the collection of short stories "Back to the Dark Night", the characters in Bola? o’s novels still retain the background color of wanderers, but their identities and appearances have become more diverse. On Friday night, writer Zhao Song and writer and translator btr will visit Lujiazui Reading Club, starting from Return to Night, and take everyone to explore Bola? o’s literary universe.

Shanghai | If you don’t come, it’s going to snow —— Sharing Meeting of Mr. Mu Xin’s Chronicles

Time:June 25th (Friday) 19:00-21:00.

Location:Sinan Bookstore, No.517 Fuxing Middle Road, Huangpu District

Speaker:Xia Chunjin (scholar, reading promoter)

On the evening of June 25th, Xia Chunjin, the author of Mr. Mu Xin’s Chronicles, will be a guest at Sinan Bookstore, taking you to read this masterpiece of Mu Xin’s research, which has accumulated for eight years, and taking readers back to Mu Xin’s life.

Shanghai | The Blooming Moment of Daily Life —— A New Book Sharing Meeting of Little Sisters by Huang Yongmei

Time:June 26th (Saturday) 14:00-16:00.

Location:Sinan Literature House, No.505 Fuxing Middle Road, Huangpu District

Guest:Huang Yongmei (novelist), Guo Shuang (writer), Huang Dehai (deputy editor-in-chief of Sinan Literature) and Fang Yan (deputy editor-in-chief of Sinan Literature)

Daily hardships and difficulties, inner distance and longing often constitute a double-line narrative in Huang Yongmei’s novels, which makes her daily life look vast and Shu Lang, like a fierce and enthusiastic aunt, a persistent and sensitive female writer, a wandering and tenacious father … It is difficult for us to fix a face for Huang Yongmei’s stories. We can only say that this is life itself. In the 21st-century literary novels, in which gender is gradually abandoned, and under the tide of Internet culture, mature female writers represented by Huang Yongmei are trying to go deep into the vast spiritual world in the new century and hold up a changeable and determined world. On the afternoon of June 26th, Huang Yongmei will take her latest anthology of novels, Little Sisters, and discuss those blooming moments of daily life with writer Guo Shuang, critics Huang Dehai and Fang Yan.

Philosophy Course in Shanghai | Downtown (I) —— Philosophy in China: Past, Present and Future

Time:June 26th (Saturday) 14:00-16:00.

Location:No.333 Huaihai Road, Huangpu District Xintiandi F4 Shanghai Sanlian Bookstore READWAY

Guest:Peng Guoxiang (seeking truth from distinguished professor, Zhejiang University), Sun Xiangchen (Dean and Professor, School of Philosophy, Fudan University) and Liu Liangjian (Dean and Professor, Department of Philosophy, East China Normal University).

Philosophy begins with curiosity, and everyone is a philosopher when looking up at the stars; Philosophy grew up in the city, and Socrates laid the foundation of philosophy in the noisy market of Athens. Philosophy is around us, and everyone has their own understanding of the world more or less. Even in this bustling downtown, we know that you care about more than the immediate prosperity. On the afternoon of June 26th, the first lecture of a series of lectures on "Philosophy in the Downtown" was given by Peng Guoxiang, a teacher from Qiushi distinguished professor, Zhejiang University. Not long ago, he just published a masterpiece "Methodology of China Philosophy: How to Treat" China Philosophy "; The two guests were Professor Sun Xiangchen, Dean of the School of Philosophy of Fudan University, and Professor Liu Liangjian from the Department of Philosophy of East China Normal University. The theme will revolve around the proposition "China’s Philosophy".

Shanghai | The Integration of Shanghai Culture and Jiangnan Culture

Time:14:00 on June 26th (Saturday)

Location:Academic lecture hall on the third floor of Putuo District Library, No.1800 Daduhe Road, Putuo District

Speaker:Cherish Jane (writer)

Cities have temperatures, blocks are suitable for walking, and buildings can be read. When we walk around the block and read the buildings, we can feel the foreign-style Shanghai in people’s eyes everywhere. In fact, it is also full of strong Jiangnan customs, which are covered by the buildings themselves and endowed by people living in them. This is unique to Shanghai, which is full of rivers and rivers, and is also created by Shanghai’s urban spirit. In this lecture, Shanghai writer Xi Zhen talks with you about the integration of Shanghai culture and Jiangnan culture.

Shanghai | Left-handed Finance, Right-handed Love —— The Press Conference of the New Book Between Rise and Fall

Time:June 26th (Saturday) 14:00-15:30.

Location:No.1834 Huaihai Middle Road, Xuhui District -1 Dayin Bookstore

Guest:Bei Bei (college teacher), Mu Ye (literary critic and poet), Wu Mei (editor-in-chief of Shanghai Education Press) and Ge Shuyi (novelist)

From the perspective of Shanghai World Financial Center, Beibei’s Between Ups and Downs depicts the bitter ups and downs in the financial market. On June 26th, we will hold "Left-handed Finance, Right-handed Love —— Between the Ups and Downs" in Wu Kang Road Store of Da Yin Bookstore to discuss the new form of social life under the financial wave.

Shanghai | Xu Guangqi and the Great Changes in the Late Ming Dynasty

Time:June 26th (Saturday) 14:00-15:30.

Location:Multi-function Hall, Building B, China Publishing Lanqiao Creative Industrial Park, No.838 Guangji Road, Hongkou District

Speaker:Jia Xuefei (Deputy General Manager, Shanghai Juzhen Company, Zhonghua Book Company)

As a scholar who grew up in the traditional society of China, Xu Guangqi paid attention to the practice of solving people’s livelihood problems in the process of taking the imperial examination, treated the emerging western science and technology with an open mind and a pragmatic attitude, and tried to integrate it into Chinese culture for our use. The late Ming Dynasty experienced the first step of China’s integration into the world, which prompted a great change in the late Ming Dynasty, and Xu Guangqi was one of the representatives who promoted this change.

The Pure Confucian Style in Shanghai | Tang Poetry

Time:14:30 on June 26th (Saturday)

Location:China Space, 18th Floor, Xinhua Center, No.331 Caoxi North Road, Xuhui District

Speaker:Chen Shangjun (Professor, Chinese Department, Fudan University)

Professor Chen Shangjun specializes in literature and classical philology of Tang and Song Dynasties. He has devoted much effort to the collection and textual research of literature in Tang Dynasty and the study of writers’ lives and works in Tang and Song Dynasties. He is also engaged in the study of historical philology and stone carving philology. This Xinhua Zhiben Reading Club invited Mr. Chen Shangjun to give a lecture on the mellow Confucian style in Tang poetry.

Shanghai | On Zhang Liang’s Knowledge Structure and the Essentials of Taigong’s Art of War —— Reading Historical Records: A Family Leaving Hou’s Family

Time:June 26th (Saturday) 15:00-16:30.

Location:Zhida Bookstore, Floor 1.5, Fuhua Science and Technology Building, No.525 Guoquan Road, Yangpu District, Activity Space

Speaker:Zhang Wenjiang (School of Humanities, Tongji University, distinguished professor)

In this lecture, Professor Zhang Wenjiang, a guest, will discuss the knowledge structure of Zhang Liang, the first hero of the Western Han Dynasty, and discuss the spread and essence of The Art of War, so as to understand what my father taught me.

Shanghai | "True" and "False" Novelists —— Sharing Meeting of Double Time: Dialogue with Western Literature

Time:June 26th (Saturday) 15:00-17:00.

Location:4F Biography Library of Investment Press was built on the first floor of Jiayu Building, Building 8, No.18 Gongping Road, Hongkou District.

Guest:Bai Lin (cultural journalist and writer) and Zhao Song (writer)

In "Double Time", Berlin asks questions to dozens of writers who are well-known in the contemporary literary world, but not only talks about literature with them, but also often "wanders into social issues and moral issues". She not only pays attention to the writers’ status as "writers", but also presents readers with their diverse faces as humanists, investigative journalists, critics and even political participants, and their views on the world through these faces. For Zhao Song, the novel itself contains infinite possibilities. In this world, he is an "architect", constantly trying to build a new reality with words; He is also a "chemist", observing the chemical reactions brought about by fresh word combinations. On the afternoon of June 26th, Jiantou Bookstore, in conjunction with movable type culture, invited Bai Lin, who had interviewed many novelists, and Zhao Song, a novelist, to visit Jiantou Bookstore and Shanghai Pujiang Store to have a talk on the topic of "True and False Novelists". The so-called "truth" and "falsehood" are not meant to define "writer", and it is even possible that this dialogue will make this identity more chaotic.

Shanghai | Dialogue between Tea and Porcelain —— Sharing Meeting of the New Book "Fundamentals of Tea"

Time:June 26th (Saturday) 15:00-16:30.

Location:Da Yin Jing She, No.308 Chongqing South Road, Huangpu District

Guest:Zhou Zhonglin (tea culture scholar) and Tu Ruiming (ceramic culture researcher and writer)

As we all know, tea begins with Lu Yu’s Tea Classic. The Book of Tea is the earliest, most complete and comprehensive monograph on tea in the world, and is known as the "encyclopedia of tea". The production of tea utensils is inseparable from ceramics. Tea and porcelain are both the essence of Chinese civilization and China’s great contribution to world material civilization, and they are closely related. On June 26th, Mr. Zhou Zhonglin, a well-known tea culture scholar and spokesperson of Yuncha, and Mr. Tu Ruiming, a well-known porcelain person and ceramic culture researcher, will visit Da Yin Bookstore and bring us their in-depth interpretation of the topic of tea and porcelain.

Shanghai | How to deal with yourself in the technological age

Time:10:30 on Sunday, June 27th.

Location:The bookstore 2F at the foot of the mountain, No.58 Foshan Road, Songjiang District.

Guest:Yang Qingfeng (Professor, Research Center for Biomedical Ethics, Fudan University), Yan Hongxiu (Professor, Institute of Science History and Science Culture, Shanghai Jiaotong University), Duan Weiwen (Researcher, Institute of Philosophy, China Academy of Social Sciences) and Liu Yongmou (Professor, School of Philosophy, China Renmin University).

Enjoy the consequences of technology, or give up the convenience of technology, everyone living in modern society, I’m afraid there is no choice-technology, agent of a variety of lifestyles. Yang Qingfeng, Yan Hongxiu, Duan Weiwen and Liu Yongmou, the professionals of philosophy of technology, are willing to talk about people in the future of technology in a semi-serious and semi-ridiculous way. They thought about 8 topics and wrote 32 semi-propositional compositions, expressing their similar or opposite views and wrestling with each other. This group of articles, some of which have been published in "澎湃 Ideological Market", has a click-through rate of 1 million+under the internet technology. Now several authors have compiled these articles into a small book. On the morning of June 27th, at the bookstore at the foot of the mountain (Foshan Road Store), please listen to their topic: the technological age and human enhancement.

Shanghai | The vast sea in the heart, who is alone with the sail-Saito Maoji and his short songs　

Time:June 27th (Sunday) 14:00-15:30

Location:Shanghai Library, No.1555 Huaihai Middle Road, Xuhui District, 3F creates a new space.

Speaker:Gao Haiyang (poet and translator)

"Short Song" began in the 6th and 7th centuries, and it is one of the many poetic styles of Japanese Wakayama. In modern times, many singers tried to innovate the traditional harmony songs. Shigeyoshi Saito is one of the leading figures in the modernization of short songs, and later has the reputation of "the sage of modern songs". On the afternoon of June 27th, Mr. Gao Haiyang, the translator of the first Chinese version of Shigeyoshi Saito’s short song anthology "My heart is still like a distant mountain fire: Shigeyoshi Saito’s short song 300", will be a guest at the sharing meeting of the above picture, reading the short song and haiku, the life of Shigeyoshi Saito, and his short songs full of emotion and tension, so as to lead readers to appreciate the red light shining in modern Japanese poetry circles.

Shanghai | 1908-1925 —— The violent age when hundreds of rivers returned to the sea.

Time:June 27th (Sunday) 14:00-16:00

Location:4F Biography Library of Investment Press was built on the first floor of Jiayu Building, Building 8, No.18 Gongping Road, Hongkou District.

Speaker:Wang Weiming (writer, urban culture critic)

On the afternoon of June 27th, Jiantou Bookstore, together with Shanghai Shuangping Charity Foundation, invited Wang Weiming, a writer and critic of urban culture, to visit Jiantou Bookstore, Shanghai Pujiang Store, to unveil the historical features of the radical era from 1908 to 1925, to depict the figures in the background of the changing era, and to tell the evolution of ideological trend in the awakening era.

Shanghai | Re-understand "West" and "Modern"

Time:June 27th (Sunday) 19:00-20:30.

Location:4F Biography Library of Investment Press was built on the first floor of Jiayu Building, Building 8, No.18 Gongping Road, Hongkou District.

Guest:Liu Qing (Professor, Department of Political Science, East China Normal University), Zhang Xiaoyu (Researcher, Center for World Politics Studies, East China Normal University) and Ming Jiang (Historian).

How should we re-recognize and re-position the "West"? What happened in the west in the first 20 years of the 21st century, and what will happen in the future? This is discussed by Professor Liu Qing, a highly acclaimed tutor of Qipa Theory, in his new book "The West since 2000". Today in history, do we subconsciously think that the premise of "what is modern" is clear, the content already exists, and the benchmark has lived in reality? Zhang Xiaoyu, a young political scientist, put forward such a question in his new book Technology and Civilization: What exactly is a modern society? How did modern society come into being? Will different understandings of modern society tear the world apart? On June 27th, Jiantou Bookstore jointly invited Professor Liu Qing, the tutor of Qipa Shuo, Zhang Xiaoyu, a young political scientist, and Ming Jiang, a well-known historical scholar, to visit Jiantou Bookstore, Shanghai Pujiang Store, to share their observations on the West and their understanding of modern society over the years.

Chongqing | Towards Reproduction: Why Does Writing Survive?

Time:15:00 on Friday, June 25th.

Location:Wisdom Classroom, Floor 2, Building D, sichuan fine arts institute Design Institute, No.28 University Town South Road, Shapingba District

Guest:Bei Xiaorong (lead writer of Sanlian Life Weekly) and Pu Shi (lead writer of Sanlian Life Weekly)

Literature may belong to writers, but writing should belong to everyone. Today, new technology seems to bring diversified possibilities to writing. From blog to Weibo, online literature and artificial intelligence writing, writing has become more attractive. However, the technology and process of this production are still firmly controlled by the system, that is to say, under this more detailed control, writing (production) will inevitably lead to a boring. Why does writing survive? It seems to be urgent. Therefore, we look forward to becoming a real writer, to regain possession of these technologies and processes, and thus to reproduction.

Hangzhou | The Miracle of Language —— A New Book Sharing Meeting of HanDong’s Miracle

Time:June 26th (Saturday) 14:30-16:30

Location:One-way space 2F, B201, Yuanyang Ledigang Cultural Experience Zone, No.58 Lishui Road, Gongshu District

Guest:HanDong (poet and novelist), Potato Brothers (poet), Fang Xianhai (poet and artist) and Yuan Wei (poet and artist).

What is the way of nature? What is the way of poetry? How to write "the artificial language of nature" On June 26th, HanDong will take the latest collection of poems "Miracle", which was launched after six years, and visit Hangzhou Ledigang Store with the poets Potato Brothers, Fang Xianhai and Yuan Wei to talk about the latest achievements of this poem creation and language exploration. Talk about the use of concrete, simple and clear words in poetry writing; Talk about the miracle of poetry created by language skills.

Hangzhou | Not Lagging Prophecy —— A B’s New Book Sharing Meeting of "The Liar Comes to the South"

Time:June 26th (Saturday) 19:00-21:00

Location:One-way space 2F, B201, Yuanyang Ledigang Cultural Experience Zone, No.58 Lishui Road, Gongshu District

Guest:A Yi (writer), Guo Honglei (professor and doctoral supervisor of School of Humanities, Hangzhou Normal University), Lv Yanlin (lecturer of School of Humanities, Hangzhou Normal University) and Xu Zhaozheng (doctor of Beijing Normal University).

In 2019, after writing the novella "The Liar Came to the South", A B defined it as: a lagging reflection of the social fact that the liar became a disaster. In 2021, A Yi found that fraud was still rampant, and the swindlers even had a great readiness to fight with us for a long time. This novel became a "not lagging prophecy". On the evening of June 26th, novelist A Yi took his new book "Liars Come to the South" as a guest in one-way space, and shared the contents of the new book and "not lagging behind" with scholars such as Guo Honglei, Lu Yanlin and Xu Zhaozheng.

Hangzhou | Peach Blossom Fan and The Lancet —— A New Book Sharing Meeting of My Sea: Selected Poems of Zhu Zhu　

Time:June 27th (Sunday) 14:30-16:30

Location:One-way Space B201, Yuanyang Ledigang Cultural Experience Zone, No.58 Lishui Road, Gongshu District

Guest:Zhu Zhu (poet) and Jiang Weak Water (poetry critic)

Zhu Zhu formed his elegant, subtle and restrained style in the 1990s. After entering the new century, his inner lyricism blended narrative, drama and other artistic elements. Through a series of more creative texts, he conveyed the depth of personal experience and the breadth of collective memory in the context of historical changes and contemporary life. In 2021, Yazhong Poetry Collection newly published the first anthology of Zhu Zhu’s 30-year writing-"My Sea: Selected Poems of Zhu Zhu". On the afternoon of June 27th, the poet Zhu Zhu and the poetry critic Jiang Ruanshui will visit the One-way Space Hangzhou Ledigang Store, and take this anthology of poems as the thread to lead everyone into Zhu Zhu’s poetry world.

Hangzhou | Restatement of the Basics of China Tea —— A New Book Sharing Meeting of the Basics of Tea in Zhou Zhonglin

Time:June 27th (Sunday) 19:00-21:00.

Location:One-way space 3F, B201, Yuanyang Ledigang Cultural Experience Zone, No.58 Lishui Road, Gongshu District, literary scene

Guest:Zhou Zhonglin (tea culture scholar) and Pan Cheng (scholar and writer)

Lu Yu wrote Tea Classic in order to liberate tea from the secular way of eating, while Zhou Zhonglin wrote The Basics of Tea in order to regain the elegant tradition of tea in China and spread the tea culture in China. On the evening of June 27th, Zhou Zhonglin, a scholar of tea culture, and Pan Cheng, a scholar and writer, visited Hangzhou Ledigang Store, a one-way space, to talk about the enlightenment of Lu Yu’s Tea Classic and trace back to the source of tea culture in China.

Nanjing | Happy birthday, little prince-Saint Exupery’s birthday commemoration

Time:19:00 on Friday, June 25th.

Location:Pioneer bookstore, No.173 Guangzhou Road, Gulou District

Guest:Huang Hong (Professor, Doctoral Supervisor, French Department, Nanjing University), Dan Hansong (Professor, English Department, Nanjing University), Qin Wen (Lecturer and Translator, School of Foreign Languages, Nanjing University)

June 29th is the birthday of Saint Exupé ry, a famous French writer. The Little Prince written by him has been translated into more than 300 languages and touched countless hearts. On the evening of June 25th, Huang Yong, a professor of French Department of Nanjing University, will visit pioneer bookstore with his translations The Little Prince and The Encyclopedia of the Little Prince, and The Stars and Roses of the Little Prince: A Biography of Saint Exupé ry by Schiff, a Pulitzer Prize winner, to review the romantic life of Saint Exupé ry and share the depth of his works.

Nanjing | past lives of Xuanwu Lake —— Looking at the historical context of Xuanwu Lake from the evolution of its name

Time:June 27th (Sunday) 14:00-15:30

Location:Building 16, Yuedong Xinmenxi, No.52 Fengyou Temple, Qinhuai District, Xiaoshuguan

Speaker:Huang Yongwu (former member of the Development Research Office of Xuanwu Lake Management Office)

In the long history of nearly two thousand years, Xuanwu Lake has become a hotbed of culture and art, which has had a certain impact on the historical and cultural development of Nanjing. Many people of the hour have left immortal legends and poems for Xuanwu Lake. On June 27th, Big Roof Culture invited Huang Yongwu, a former member of the Development Research Office of Xuanwu Lake Management Office, to visit Nanjing Xiaoshu Library, and "look at the historical context of Xuanwu Lake from the evolution of its name" with readers on the theme of "past lives of Xuanwu Lake".

Nanjing | Meiyuan Classic Reading Group No.34: "Nine Kings Seize the Office"

Time:June 27th (Sunday) 15:00-17:30

Location:Wanxiang Bookstore, No.8 Jinyinjie, Gulou District

Speaker:Zheng Xiaoyou (Deputy Research Librarian of National Library), Li Xiaobo (Lecturer of History Department of Nanjing Normal University) and Xia Xia (History and Culture Lover).

"Nine Kings Seize the Office" is Dr. Zheng Xiaoyou’s third popular reading of political history in Qing Dynasty, which is a bridge between academic history research and public history reading. Behind it is the author’s desire to break the shackles of people’s procedural and facebook thinking when observing history, which is admirable. The thirty-fourth salon of Meiyuan Classic Reading Group will focus on this book by Zheng Xiaoyou.

Xi ‘an | Research on Ancient Stone Inscriptions and Medieval History of China in Japanese Collection.

Time:June 25th (Friday) 19:00-21:00.

Location:Meeting room (Room 1-11) on the first floor of History College, History Building, Chang ‘an Campus, Northwest University, No.1 Xuefu Avenue, Chang ‘an District

Speaker:Xia Yan (Professor and Doctoral Supervisor, School of History, Nankai University)

Professor Xia Yan’s main research directions are social history, environmental history and institutional history of Wei, Jin, Southern and Northern Dynasties, Sui and Tang Dynasties. In the fourth lecture of "Chen Zhi Memorial Lecture", we invited Professor Xia Yan to give a lecture on the ancient stone carving materials in China and the study of medieval history.

Xi ‘an | Awakens the warm memory of food and local conditions.

Time:June 26th (Saturday) 15:00-17:00.

Location:SKP RENDEZ-VOUS, activity area, 9th floor, Xi ‘an SKP Shopping Center, No.261 Chang ‘an North Road, beilin district.

Guest:Zhu Xuedong (freelance writer and columnist) and Duan Wanjin (lawyer)

The taste of Jiangnan drifting away, the simple love and affection for food and dishes, the respect and admiration for nature in seasonal solar terms, and the feedback from nature to people’s tenacious will to survive continue from life to this book "People’s Diet". What’s your favorite food after climbing mountains and crossing the sea? What are your childhood memories? In the land of Guanzhong, where the wine is warm and the ears are hot, which store do you often drink and chat with your friends? On June 26th, Zhu Xuedong will take his new book "People’s Diet" to visit SKP RENDEZ-VOUS in Xi ‘an, and show us his food map, hometown food notes and private food list.

Xi ‘an | Cross-cultural Dialogue: From Fudan to Oxford —— Sharing Meeting of Oxford Notes in Xi ‘an

Time:June 26th (Saturday) 19:00-20:30

Location:SKP RENDEZ-VOUS, activity area, 9th floor, Xi ‘an SKP Shopping Center, No.261 Chang ‘an North Road, beilin district.

Guest:Zhang Lifen (Professor and Doctoral Supervisor of School of Journalism, Fudan University), Xu Jiabiao (Vice President, Professor and Doctoral Supervisor of School of Journalism and Communication, Shaanxi Normal University), Liu Xiaorong (writer and media person).

Different from other notebook works, Zhang Lifen’s Oxford Notes has brought us a long-lost stranger experience. His language is like floating ice in the sea of Wang Yang, which is fragmented, warm and eloquent at the same time. By reading his words, we can feel his lovely soul and broad vision. On June 26th, Zhang Lifen, the author of the new book "Oxford Notes", talked with guests Xu Jiabiao and Liu Xiaorong about Britain and Oxford that you didn’t know, and shared the story behind the creation with readers.

Xi ‘an | Drama and Movies —— Reasons for the Beginning of 13 Stories

Time:June 26th (Saturday) 19:00-20:30

Location:SKP RENDEZ-VOUS, activity area, 10th floor, Xi ‘an SKP Shopping Center, No.261 Chang ‘an North Road, beilin district.

Guest:Gong Yeqian (screenwriter and director) and Xia Ci (screenwriter and director)

On June 26th, we invited playwright and drama director Gong Yeqian and Xia Ci. They will compare and analyze the opening ways of quentin tarantino’s works and many other drama works, a legend in film history, so as to let everyone participate in it and feel the corresponding embodiment of the opening ways of the film in the drama on the basis of demonstrating examples.

Xi ‘an | Restoring the Gorgeous World of the Ancient People —— Sharing Meeting of New Books of Beauty Map and Interesting Archaeology

Time:June 27th (Sunday) 14:00-16:00

Location:Fang Fangli Laboratory, Floor 1, Laochenggen Gpark Shopping Center, No.22 Xinghuo Road, Lianhu District

Guest:Meng Hui (researcher and writer of China traditional material culture) and Xu Weihong (researcher and writer of Shaanxi Archaeological Research Institute).

This Sunday, Meng Hui, a researcher and writer of China’s traditional material culture, will come to Xi ‘an Fangfang Bookstore with her new work "The Picture of Beauty" to understand the ancients’ pursuit of beauty from the details of ancient daily life and arouse readers’ re-imagination of classical beauty.

Chengdu | Sex and the City and Modern Life in Jin Ping Mei

Time:June 26th (Saturday) 14:30-16:30

Location:No.918, South Section 1 of Tianfu Avenue, Tianfu New District Luhu Art Exhibition Center A4 Academic Lecture Hall

Guest:Liu Xiaolei (writer) and Li Qian (vice president of App, linguist)

On June 26th, Liu Xiaolei, a writer, will take her new work "Jin Ping Mei as Desire" as a guest, and together with Li Qian, a vice president and linguist, will show you this great book of life and death of mortals. Welcome readers to read Jin Ping Mei carefully with Liu Xiaolei, see people’s hearts and gain insight into the world; Think about life and death, stay away from fear, let go of arrogance and prejudice, and gain the ability to love.

Chengdu | Creating in Travel —— Sharing the New Books of Single Reading 26 Global True Stories Collection

Time:June 26th (Saturday) 14:30-16:30

Location:No.918, South Section of Tianfu Avenue, Tianfu New District Luhu Art Exhibition Center A4 Small Theater

Guest:He Yujia (translator), Ren Ning (founder of venture capital fund) and Wu Qi (editor-in-chief of Single Reading)

Finding the topic during the trip is the favorite way of Single Reading. "Single Reading 26 Global True Stories Collection" can be said to be born by a trip. Today’s three guests are not only lovers of travel, but also beneficiaries of travel. So, is it possible to create while traveling? What kind of influence did travel bring to them? Under the epidemic, how did they change the direction of travel and what new discoveries did they make? On the afternoon of June 26th, let’s talk about travel and creation together.

Chengdu | There is a bright future hidden in science fiction.

Time:June 27th (Sunday) 14:30-16:30

Location:Qingyang District Kuanzhai Lane No.30 Sanlian Taofen Bookstore

Guest:Yu Xiyun (editor of cultural English book in Baguangfen) and Tian Xinghai (editor of cultural literature in Baguangfen and author of science fiction)

On June 27th, Dai Haoran, a senior sci-fi editor, will invite Tian Xinghai and Yu Xiyun, editors of "The Inheritor of the Stars", to reveal the origin of human civilization for you. What kind of future are we going to? We are still willing to believe that life will always find a way out! The driving force that drove the fish to climb ashore hundreds of millions of years ago pushed us to struggle for a lifetime! No matter where humans come from, these billions of stars have been handed over to us to inherit!

Chengdu | "Casting Sword": A Visual Freshman of Literary Classics —— A Meeting of Picture Book Writers with Yesterday’s Wine

Time:14:30 on Sunday, June 27th.

Location:Step activity area on the first floor of Wenxuan BOOKS, Jiufang Shopping Center, No.88 Middle Section of Fucheng Avenue, High-tech Zone

Speaker:Xijiu (picture book writer)

On June 27th, the first meeting of Casting Sword was held. We invited the picture book writer-Xijiu, who took us back to Lu Xun’s classic stories with her colorful brushstrokes, to visit Wenxuan BOOKS Jiufang Store and share the mystery and novelty behind the image creation with us.

Zhengzhou | The Aesthetic World in the Shaking of Chai Skirt —— Sharing Meeting of the New Book of Beauty Map

Time:June 26th (Saturday) 15:00-17:00.

Location:Jinshui District Wenhua Road No.2 Songshe Bookstore

Guest:Meng Hui (researcher and writer of traditional material culture in China) and Li Hong (vice president of Chinese Han Painting Society)

Meng Hui’s latest work, Beauty Map, not only focuses on the clothes of ancient people, but also reveals how ancient women used aesthetic wisdom to all levels of food, clothing, housing and transportation. This Saturday afternoon, she will be a guest at Songshe Bookstore, and together with teacher Li Hong, she will explain "the aesthetic world of hairpin skirt swaying".

Zhengzhou | When Revenge and Love Meet in a Narrow Way —— Sharing Meeting of Zhi ‘an’s Novel "Being Ordered"

Time:June 27th (Sunday) 15:00-17:00

Location:Jinshui District Wenhua Road No.2 Songshe Bookstore

Guest:Zhi ‘an (writer and scholar) and Dai Dahong (translator)

Being ordered is the first novel of Zhian, which is about memory and love. Memory comes from the past and has not yet left. Love points to new life, but it cannot grow. On Sunday afternoon, writer, Zhang Ailing researcher Zhi ‘an and translator Dai Dahong will visit Songshe Bookstore to share the revenge and love in The Order with readers.

　　　　[XCAR domestic new car original]

　　　　Recently, we learned from relevant channels that the pre-sale price of FAW Toyota Corolla twin-engine model will be announced in Beijing on October 18th, and it will be officially listed on October 28th. According to the previous news, the Corolla Twin Engine Edition will launch four models, namely, Pioneer Edition, Elite Edition, Deluxe Edition and Flagship Edition.

　　　　The overall appearance of the new model is not much different from that of the current Corolla gasoline version, but it has been adjusted in many details. The design of the headlights and front bumper of the Corolla twin-engine is more dynamic, and the blue Toyota logo is also adopted to highlight its identity as a new energy vehicle.

　　　　The lines on the side of the car body run from the front of the car to the rear of the car. At the same time, the "HYBIRD" logo in the front fender and the two-color multi-spoke wheels also prove all the time that this is a new energy vehicle. In addition, the taillights in the rear of the car have been blackened to make them look more attractive.

　　　　According to previous news, the elite model is equipped with automatic headlights, leather steering wheel and leather seats; The luxury version will be equipped with LED daytime running lights, exterior rearview mirrors with automatic folding and anti-glare functions, Bluetooth, reversing images and keyless entry; The flagship model will be equipped with rain-sensing automatic wiper, 6-way electric adjustment of driver’s seat, front seat heating, multimedia navigation, cruise control and other configurations.

　　　　In terms of power, according to the logo provided by the Ministry of Industry and Information Technology, the car will adopt the same power system as the current Prius, consisting of a 1.8L Atkinson gasoline engine and an electric motor, with a maximum power of 73kW(99Ps). The transmission part will match the E-CVT gearbox. In addition, the comprehensive fuel consumption per 100 kilometers is 4.9L/100km.

　　　　Editor’s comment:Toyota has always been a maverick to engage in new energy vehicles, others engage in plug-in/pure electricity, and it engages in mixing; Others also engage in plug-in, and it engages in fuel cells. I really admire Toyota’s spirit! Oh, yes! It is said that the pre-sale of this car starts from 150 thousand yuan, which is very competitive!

Related content review:

FAW Toyota New Land Cruiser News or Listed at the End of the Year

　　Household medical devices sell well and become one of the pillars of pharmacy performance.

　　Consumers "place an order with one click" to purchase medical devices online? A little carelessness may lead to risks. According to media reports, a man recently bought a circumcision device online, and he was eventually sent to hospital for treatment because of his improper operation. The reporter visited a number of e-commerce companies and found that there are different brands and different prices of such products on sale in the market, but the stores have different attitudes towards the instructions and risk warnings of such medical device products. In this regard, some insiders reminded that the e-commerce platform has irregular problems such as unclear products for medical devices, no relevant business qualifications and risk-free tips. Consumers should be more vigilant when shopping online.

　　Text/Figure Guangzhou Daily All-Media Reporter Tu Duanyu Wenjing

　　Case: There are safety risks in surgical instruments at home.

　　A few days ago, a report aroused social concern — — A man in Shenzhen, Guangdong Province, was busy with his work. He circumcised himself at home by online shopping, and was sent to hospital for treatment because of improper operation, which caused bleeding in his lower body. The doctor reminds: Improper self-circumcision has the risk of necrosis. Although this kind of surgery is minor in medicine, it does not mean that ordinary people can do it at home. It has certain safety risks and may be accompanied by bleeding, wound infection and abnormal appearance. It is necessary to go to a regular hospital for professional treatment.

　　It is reported that the circumcision device is a surgical instrument, which belongs to the second category of medical devices and is sold on all major e-commerce platforms.

　　Reporters in JD.COM, Taobao, Pinduoduo and other mainstream e-commerce platforms found that the price of circumcision is mostly in the range of 100~300 yuan. When the reporter consulted an online shop, the customer service said: "There is no risk"; The customer service of another online shop stressed: "We are fully qualified and can deliver goods at any time", but it did not show relevant qualification certificates. The page of an online shop on the shopping platform indicates: "This product is only used by professional doctors and medical institutions, and ordinary individual consumers do not deliver it." The customer service told reporters that it is necessary to have a doctor’s license to deliver it. The backstage of another online shop also reminded that this product can only be operated by professional doctors, but when the reporter asked if it could be shipped after being photographed, the customer service said yes.

　　Investigation: Some nose-clip snorers and laser hair removal devices are not clearly defined as medical devices.

　　The reporter browsed the major e-commerce platforms and found that electronic sphygmomanometer, oximeter, oxygen generator, infrared physiotherapy lamp, snorer and sputum aspirator are the main products of online shopping medical devices. In fact, however, the Catalogue of Medical Devices clearly states that snorers, ventilation nasal patches and so on, which can improve snoring or dilate nostrils by dilating nasal cavity, maxilla and mandible or correcting them, belong to the second category of medical devices.

　　The Catalogue of Medical Devices shows that the semiconductor laser hair removal instrument belongs to laser therapy equipment and is the third kind of medical devices, but the intense pulsed light hair removal instrument belongs to the second kind of medical devices. In 2018, National Medical Products Administration issued the Notice on Classification and Definition of High-intensity Pulsed Light Hair Removal Products, indicating that high-intensity pulsed light hair removal products are managed according to Class II medical devices. If an unqualified enterprise sells such products, the regulatory authorities may punish it for unlicensed sales or out-of-range operations.

　　The reporter saw in Taobao that there are many kinds of household intense pulsed light hair removal instruments on sale, including Braun, Philips, Mujin and other big brands.

　　When the reporter asked the customer service of a brand flagship store whether the products on sale belonged to medical devices, the customer service said that this was a household depilation instrument. It is reported that according to the regulations, since January 1, 2023, products of intense pulsed light hair removal may not be produced, imported or sold without obtaining the medical device registration certificate according to law. Some insiders said that home hair removal instruments are mainly sold online, and how to obtain the registration certificate of medical devices is an urgent problem for brand enterprises.

　　National Medical Products Administration: Some medical beauty products are managed by medical devices.

　　According to industry data, the consumption ratio of household medical devices and medical devices in China is about 1: 4 at present, while it is generally about 1: 1 in developed countries. There is a large market space for household medical devices, and the demand scale of household medical devices will continue to grow in the future. A person in charge of a chain pharmacy in Guangzhou told the reporter that household medical devices contributed one-third of the pharmacy’s performance, including blood pressure detectors, blood sugar detectors, electronic thermometers, foot physiotherapy devices and so on.

　　In the face of endless chaos such as product abuse and out-of-range use, China is constantly strengthening supervision and clarifying the "concept" from the source. Just recently, National Medical Products Administration issued the Announcement on Adjusting Some Contents of the Classified Catalogue of Medical Devices to adjust the contents of the Classified Catalogue of Medical Devices for 27 types of medical devices. The adjustment contents announced this time include some medical beauty products, such as RF therapeutic devices and RF skin therapeutic devices, which are clearly regulated according to Class III medical devices; Facial embedding line and facial lifting line shall be supervised according to Class III medical devices. According to the Regulations on the Supervision and Administration of Medical Devices, products that have not obtained the registration certificate of medical devices according to law will not be allowed to be produced, imported or sold.

　　Little knowledge: medical devices are divided into three categories according to risks.

　　It is reported that at present, China implements classified management of medical devices according to the degree of risk. Risks are divided into three categories from low to high:

　　The first category is medical devices with low risk, which can be guaranteed to be safe and effective by routine management;

　　The second category is medical devices with moderate risks that need strict control and management to ensure their safety and effectiveness;

　　The third category is medical devices with high risks and need to take special measures to strictly control and manage them to ensure their safety and effectiveness.

　　According to the Regulation on the Supervision and Administration of Medical Devices, those who engage in the operation of Class III medical devices shall apply for a business license and submit relevant materials to the department in charge of drug supervision and administration of the local municipal people’s government with districts. It is the obligation stipulated in the Measures for the Supervision and Administration of Online Sales of Medical Devices to publish true product information when selling medical devices.

Original Cell Press CellPress cell science

life sciences

Life science

Fibroblasts are diverse interstitial cells, which create signal niches by producing complex extracellular matrix and biophysical and biochemical clues, and participate in tissue balance and diseases. Fibroblasts have diverse lineages and a wide range of uses, but our understanding of these cells, which fill a considerable part of the human body, is still not comprehensive. Next, let’s understand the mysterious and fascinating fibroblasts from four aspects and embark on a human journey across time and space.

Definition of fibroblast

The term "fibroblast" refers to the following kinds of cells: (1) cells that secrete many macromolecules with the same structure and signal as the extracellular space of tissues; (2) Adopting the phenotype of myofibroblasts that contract instantaneously when dealing with tissue injury; (3) signal niche cells as resident stem cells; (4) As the progenitor cells of specialized differentiated interstitial cells, they are sometimes called mesenchymal stem cells (Lemos and Duffield, 2018; Pittenger et al. , 1999, 2019）。

Fibroblasts create and maintain anatomically diverse connective tissue rich in extracellular matrix (ECM) to support a wide range of basic organ functions, such as resisting blunt and sharp skin injuries, stretching and elastic retraction in the organ range of lung, etc. In addition to producing connective tissue, fibroblasts serve as the progenitor cells of specialized interstitial cell types during embryonic development, adult homeostasis, injury, repair and remodeling, such as osteoblasts forming bones or fat cells filled with lipids.

The origin and development of fibroblasts

In 1858, German pathologist Rudolf Virchow first described fibroblasts as a unique cell type, which he called "Spindelzellen des Bindegewebes"-"Spindle cells of connective tissue" (Virchow, 1858；; Fig. 2A). Ernst Ziegler first put forward the term "fibroblast" to describe cells that produce new connective tissue after healing (Ziegler, 1895；; Fig. 2B), this observation was replicated by Santiago Ramón y Cajal, who observed that "célula fusiforme" or "fibro-células" are important producers of granulation tissue in skin wound healing and scar (Cajal, 1986；; Fig. 2C). The appearance of in vitro technology developed in the 1900 s promoted the research of fibroblasts. These methods allow primary fibroblasts from embryonic chicken heart explants to be cultured, and these cells can easily propagate before other cell types after passage (Burrows and Neymann, 1917; Carrel, 1912; Ebeling, 1913; Hogue, 1919； Fig. 2D). More than 50 years later, 3T3 fibroblast cell line from mouse embryo was established (Todaro and Green, 1963; Todaro and others,1964) further promoted our understanding of the biological and genealogical potential of fibroblasts. These findings include the identification of fibroblast growth factor (FGFS) (Gospodarovicz, 1974); Multi-line differentiation of cultured fibroblasts into bone, cartilage and fat cells (Junker et al., 2010); And the key role of fibroblasts in the production, remodeling and contraction of ECM.

Although there are a lot of studies on fibroblasts in vitro, the in vivo correlation of these cells is still unclear, and the real characteristics of fibroblasts and their pedigree potential in the in vivo primary environment have only recently been deeply explored. New evidence shows that fibroblasts have promoted major changes in the tumor-related environment, which has been widely reviewed elsewhere (Sahai et al., 2020).

Organ specificity of fibroblasts

The existence of tissue-specific fibroblast function and lineage can support the development, homeostasis and repair needs of specific organs. During embryonic development, multiple cell lines coalesce to form fibroblasts, which are filled with organs from all three somatic germ layers, such as skin and breast derived from ectoderm, skeletal muscle or myocardium derived from mesoderm, and lungs derived from endoderm. When fibroblasts proliferate in specific organs, they will produce unique microstructure, biophysical and biochemical components of connective tissue.

In organs rich in epithelial cells (for example, skin and lungs), fibroblasts in the skin produce a mechanically elastic, viscous and elastic structural foundation, which supports the epithelial cells of the outward layered epidermis and its many appendages, mainly hair follicles and sweat glands. Fibroblasts and other mesenchymal cell lines in the skin have established three anatomically different layers: papillary dermis, reticular dermis and dermal white adipose tissue (dWAT) (Figure 5A). Skin epithelial cells are derived from ectoderm, which has a unique level of connectivetissue. In contrast, lung epithelium originated from endoderm, forming a highly branched tree and eventually forming an inflatable sac called alveoli. The gas exchange function of lung depends on the close physical connection between alveolar epithelium and extensive capillary network, and on the repeated and rapid expansion and contraction ability of lung. These functions require the reticular ECM of the lung, which has the best viscoelasticity, but is strong enough to withstand the change of air pressure and prevent alveolar rupture and potentially fatal air pressure trauma. With the maturity of the lung, the lung mesenchymal progenitor cells assume different spatial positions and functions, including smooth muscle cells around bronchi and blood vessels, pericytes, numerous interstitial fibroblasts, adipocytes supporting lung cells and mesothelial cells of visceral pleura (Peng et al., 2013; Fig. 5B).

In interstitial organs (such as skeletal muscle and heart), unlike skin and lung, skeletal muscle has no epithelial structure, but is composed of large, highly differentiated and multinucleated muscle fibers arranged in parallel, and its main function is to generate strength through contraction. The connective tissue in muscle has a complex layered tissue. Its innermost layer is called endocardium, which surrounds a single muscle fiber and contains a special basement membrane rich in laminin and collagen IV. Laminin acts through its transmembrane receptor, helping the mechanical force to be transmitted from the intracellular contraction device to the inner muscle layer rich in collagen I and III (Chapman et al., 2016). Muscle fiber group is called bundle, surrounded by perimuscular layer, which forms a continuum with tendon, and is rich in so-called perimuscular layer "cable", that is, thick connective tissue bundle mainly composed of closely arranged type I and type III collagen III fibers. Finally, the whole muscle is wrapped by the connective tissue layer of the adventitia (Chapman et al., 2016). Myocardium is an anatomically and physiologically complex contractile organ. Its main cell group, cardiomyocytes, are connected with each other, and an electrically coupled tissue is formed through the sandwich disc that constitutes its middle layer, which is called myocardium. The heart is also rich in fibroblasts, which produce and reshape a powerful ECM network, which is very important for conductivity and heartbeat rhythm. In addition to myocardium, fibroblasts also exist in the outermost epicardium, which contains specialized adipose tissue, and the innermost endocardium, with a layer of endothelial cells at its edge.Unlike most other organs’ fibroblasts, which originated from mesenchymal progenitor cells through gradual standardization, most cardiac fibroblasts are formed through EMT, and fibroblasts located in interventricular septum and right ventricle are products of EndMT (Gittenberger-de Groot et al., 1998; Fig. 5D).

Application of fibroblasts in diseases

At present, the approved anti-fibrosis therapy is aimed at the activation of fibroblasts in established diseases and cannot restore the structure and function of diseased tissues. Therefore, developing strategies to promote the repair of damaged tissues will greatly promote the development of this field.

Although the plasticity of fibroblasts may be problematic in the context of fibrotic diseases, it also provides opportunities for regenerative intervention. Recently, this understanding has promoted the development of in-situ reprogramming into fibroblasts by molecular strategy to restore tissue anatomy and function (including direct reprogramming). In skin wounds, the innate ability of fibroblasts to support hair follicle regeneration can be induced by transcription reprogramming.

Examples have proved that the principle of therapeutic reprogramming of fibroblasts in vivo can be realized in liver and heart, such as transferring transcription factors such as Foxa3, Gata4, Hnf1a and Hnf4a to myofibroblasts in liver through viruses, reprogramming them into hepatocyte-like cells, and reducing the signs of liver fibrosis in mouse models (Rezvani et al., 2016; Song et al., 2016). The above examples clearly emphasize the therapeutic potential of reprogramming tissue-resident fibroblasts directly into "working" cells, and suggest it as a new scar replacement strategy. However, there are still several important problems to be solved, including the efficiency of reprogramming factor delivery using non-integrated vectors and high fibroblast specificity (if not exclusiveness), in order to transform this attractive method into safe clinical application.

Conclusion and prospect

In the past decades, our understanding of fibroblast biology under different organs and conditions has made remarkable progress. New methods and techniques have made this field develop from phenotypic study of cultured cells more than a century ago to complex genetic and functional observation in vivo. These advances reveal that fibroblasts from different organs (such as skin, lung, heart and skeletal muscle) have unexpected similarities and unique characteristics, so they are currently used to treat human diseases.

While great progress has been made, many problems and opportunities still exist. For example, the ongoing efforts to adopt single-cell omics and space genomics technologies will provide key insights into the heterogeneity of fibroblasts within and between tissues, and their ability to assume multiple functional States for physiological or disease triggers. With our understanding of the basic function of fibroblasts far beyond the scope of ECM synthesis, in-situ regulation of fibroblasts can bring new therapeutic possibilities for a wide range of diseases characterized by aging, pathological remodeling and tissue fibrosis. New research fields, including cross-regulation between wound fibroblasts, immune cells and peripheral nervous system, are very important for understanding how to restore tissues to their pre-injury state. Finally, effective clinical transformation will require rigorous verification in local human tissues and human-like models, such as organotypic cultures, xenotransplantation and organs derived from pluripotent cells. These advances will make it possible to prevent, treat and even reverse fibrosis through proper and controlled repair.

Related paper information

The original paper was published in Cell, a periodical of CellPress Cell Press. Click "Read the original" to view the paper.

▌ Paper title:

Fibroblasts: Origins, definitions, and functions in health and disease

▌ Website of the paper:

https://www.cell.com/cell/fulltext/S0092-8674(21)00792-3

▌DOI：

https://doi.org/10.1016/j.cell.2021.06.024

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At 16: 30 on March 5, 2017, the Communist Party of China (CPC)’s outstanding party member, former deputy director of the Standing Committee of Jiangxi Provincial People’s Congress, former deputy governor of Jiangxi Provincial People’s Government, and national and provincial model worker Jiang Zhongping died in Nanchang at the age of 74.

On March 9th, Jiangxi Political Reading, an information daily, learned that Liu Chunrui, an associate professor of Chinese Department in Peking University, wrote an article recalling Jiang Zhongping’s life after learning of the death of Comrade Jiang Zhongping. With the consent of Professor Liu, we hereby forward this article.

On the Honest Life of Pioneer Jiang Zhongping

Liu Chunrui, Associate Professor of Chinese Department of Peking University.

Liu Chunrui data map

At 4: 30pm on March 5th, Mr Jiang Zhongping passed away. People are weak, which increases my sadness. The Communist Youth City, which he led the Communist Youth Reclamation Team, is located in Duchang, my hometown, separated from Poyang Lake, and looks east and west. When I was in primary school, the intern teacher told us the advanced deeds of Mr. Wang’s reform and entrepreneurship, which sowed a seed of youth for us. Last autumn, after visiting Nanchang, I was very excited to see Mr. Wang splash ink in his studio. At that time, he was still healthy and had the strength to fight the disease. Now, his sudden return to Daoshan is very painful to me. In this rather quiet midnight in the northland, sound of spring came slowly. Holding a pen, I sat in front of the window, and the bright image of my husband, aboveboard and selfless, reappeared before my eyes. With this article, I send my condolences from afar.

one

In January 1944, Jiang Zhongping was born in a poor family in Sunxiang Village, Tongzha Town, hanshan county City, Anhui Province. At the age of 10, he lost his father. At the age of 15, he took two young sisters to say goodbye to his lonely grandmother, looking for his mother, and moved to Gongqingcheng, Jiangxi. He lost his mother at the age of twenty, and joined the Communist Party of China (CPC) at the age of twenty-six. He has successively served as Party Secretary and Director of Gongqing Reclamation Farm, Deputy Secretary of De ‘an County Committee, Deputy Secretary of Nanchang Municipal Committee and Mayor, Vice Governor of the Provincial Government and Deputy Director of the Standing Committee of the Provincial People’s Congress. He has also been elected as Executive President of China Arts and Crafts Association, National Model Worker, Representative of the Eighth National People’s Congress and Representative of the 16th National Congress of the Communist Party of China. Jiang Zhongping went through hardships all his life, fought bravely and persevered, devoted all his life energy to the cause of the party and the people, and propped up the whole family with strong arms.

On the banks of Poyang Lake in 1960s, a barren land where snails were everywhere and schistosomiasis was a disaster, and a place without any marks on the map, Jiang Zhongping led the Communist Youth Reclamation Team to create a city of youth, reform and ideal. This place was named by Comrade Hu Yaobang as Gongqing Society, Gongqing Reclamation Field and Gongqing City.

The difficulty is greater than the current situation, and the reform is easy to unite the spirit. In July 1969, the Communist Youth League was forced to split up, and the Communist Youth League moved to the more desolate and remote South Lake. During the rainy season, 30,000 bricks and tiles for the covered duck factory were demolished, all of which were submerged in the huge waves. Without hesitation, Jiang Zhongping was the first to jump into the flood, but they just fished out all the bricks and tiles. That year, the salted duck factory was built, which stabilized people’s hearts and earned 90 thousand yuan, and passed the most difficult period of the farm.

He led the "Communist Youth League" to create "Duck Duck" brand down jackets and fist products such as dried salted duck, beer and lean pig, which were exported to more than 40 countries and regions, earning more than 12 million US dollars in foreign exchange each year, and the per capita output value reached more than 16,000 yuan, creating a new model of no agriculture, no work, no wealth and no business in the whole country, making the Communist Youth League "famous all over the world".

From scratch is a revolution, and everything is a realm. Every step forward, there are always storms and hardships. After the hurricane, rebuild your home; There is no town, create it yourself. In the 24th Spring and Autumn Period of the Communist Youth League, his name has been deeply engraved in this emerging city. He is like a winter plum, tenaciously blooming on the banks of the misty Poyang Lake, watching the Communist Youth League, and the fragrance overflowed in the spring of the motherland’s reform and opening up, becoming the weathervane of that era! In the face of these extraordinary achievements, he always said that this is the grace of the party, and the credit belongs to the times and the people.

Middle-aged official, performing his duties in Nanchang, cultivated for ten years, with a strong pen and heavy color, which left a good reputation. He dared to break in, transform the old city of Nanchang, build Yanjiang Road and Nanchang Bridge, and rebuild Tengwang Pavilion. He worked hard to build a new Yuzhang, repair overpasses, Changbei Airport and Economic Building. "Nanchang speed" and "Hongdu experience" became hot topics that people talked about at that time. After working in the provincial government, he still maintained a strong revolutionary fighting spirit, worked conscientiously, assisted the governor in grasping circulation, activating the market, promoting opening up, developed business with the courage of opening up, innovating and being the first, prospered the urban and rural markets, expanded inter-provincial cooperation, and worked hard for the opening up and development of Jiangxi. During his tenure at the Standing Committee of the Provincial People’s Congress, he studied the policies and business of the work of the National People’s Congress, and did some fruitful work in promoting financial and economic legislative supervision and planning and budget review. After retiring from the leadership position, he still insisted on studying, adjusted his mentality, participated in various activities within his power, and contributed to the cause of the party and the people.

In his later years, Jiang Zhongping visited the Heart Art Garden and worked tirelessly as the executive president of China Arts and Crafts Association. Grand composition, thick lines and strong brushwork are the main styles of his calligraphy and painting art. Anyone who has seen his live paintings will be amazed at the waves at the bottom of his pen and the clouds on the paper. Such artistic personality is the result of decades of entrepreneurial spirit. His pioneering will and enthusiasm for hard work have been fully demonstrated in his free art kingdom.

two

Jiang Zhongping has a general temper and dares to fight against evil forces; He is also a heavy drinker, and he will be drunk when he meets his bosom friends. He is bigger-minded, either not doing it or being the first.

He is big, as if he were born with it. In his early years, when he was herding cowboys in his hometown in Anhui, he was king of the children; Youth entrepreneurship Communist Youth League, starting from scratch to create a world; Being in charge of Nanchang in middle age has created many firsts in the whole province and even the whole country; The paintings and calligraphy in his later years are mostly large landscapes. Bamboo, only take its fresh strength; Pastoral, only praise its harvest; Autumn cliff, only painting the flying of mountain waterfalls; In the native land, "the willows on the shore are constantly looking forward, and the long Huai is thousands of miles into the new autumn", which is written about the power of clearness.

Whether starting a business or reforming, he dares to think and do it, stand tall, look far, have courage and have a big pattern. He is ahead of his ideas. When there is Poyang Lake, he will raise more ducks. When there are more ducks, he will run a dried salted duck factory. When there are more duck feathers, he will run a down factory and a winery when there are more guests.

If I read the mountain, I realized the existence of "big"; If I read the classics, I see the realm of "big". Mencius said: "Abundance is beauty, and fullness and brilliance is greatness." Zhuangzi highly praised "big", and he compared those who bear the blue sky, unique cloud spirit and are suitable for the south to Dapeng, which is a symbol of ideal personality. Adults and gentlemen are always admired by the world. Communist party people associate "greatness" with the liberation of mankind, and put the people’s cause first.

Regardless of the small, regardless of personal gains and losses. Big and magnanimous, not surprised by honor or disgrace. Big and heroic, a bright moon, remain uncorrupted. Great and fearless, fearless in times of crisis, fruitful in doing things. Big and open-minded, life and death are the same, and enlightenment is the Year of the Crane. Many of his words and deeds can be described as consistent in the "big" here.

Jiang Zhongping loves mountains, and he loves the land under his feet. He loves heaven with depth, people with temperature and children with moderation.

In May 1982, he led a delegation to Japan to study down processing technology. When I came back, the suitcase was full of all kinds of down technical data, but there was not a tight Japanese appliance. Others advised him to move to a new house, but he insisted, "I won’t be the last to move until all the employees live in the new house." I live in a low, damp old bungalow, worrying about its people and enjoying myself.

He often said that people should have spirit. The reason why the wheel of human beings rolls forward is that only by facing difficulties can it be solved. After suffering from a serious illness, his work and rest remained unchanged, his distress did not increase, he was optimistic and never bowed his head. Persuade children to say that he has been satisfied all his life, feeling grateful to the party, thanking friendship and being filial to Reiko, and there are not many regrets.

The first thing I did after waking up from major surgery was not to ask him about his illness, but to ask his classmates who came to visit him from other places. How was the arrangement? Did you not treat your friends badly? He is such a person, who cares about many people and few about himself. Many people contribute to their country, but few give to themselves. Even though he was seriously ill, he still thought very little of himself, and told his family not to cause trouble to the country. He said that things have come to this point, and the road is natural, and heaven and man are one.

People’s hearts are full of meat. Suffering from illness, there is no pain! But he has always been a strong ninja, trying not to let people find his emotional changes. I really can’t insist on going. I can only hum a few times at most. He is such a man, such a gentleman and such a true hero.

three

Jiang Zhongping has always been optimistic. In November of the year before last, when the serious illness was just found out, the doctor judged that he would not live for 9 months. After the operation in May last year, he lost a lot of weight, and when he saw his youngest son’s bloated body, he did not forget to ridicule that he still had a figure to wear clothes to be beautiful. On December 12th last year, it was his seventy-third birthday. His children were very happy and held a simple birthday party for him at home. He said that the Central Committee has eight regulations that cannot be extravagant, and then said easily: "The past year has been like a year for others, but it has been like a year for me." I hear it in my ears, but it hurts in my heart. What a powerful spiritual strength his old man must have to support such a relaxed smile.

Jiang Zhongping’s son said, "With my sick father, I have experienced what it means to race against time, and I feel that life is more and more precious, and the most rare thing is a deep affection between father and son. I really want to say to him:’ I don’t want anything. You can live, which is the greatest gift for our children.’ "

Liang Jikuan recalled that his father, Mr. Liang Shuming, said that at that time, his father’s whole task was to preserve the tradition of "gentle". He said that as long as China’s culture does not die, the nation will not die. Mr. Liang has no time to teach his children face to face and to teach them by example. But Mr. Liang Jikuan clearly saw the tall figure after his father hurried. This tall figure is the deepest thought and the most touching education.

Seek things from the overall situation, have a bright heart, be an upright person, and take great care of people. -This is the deepest thought and the most touching education that Jiang Zhongping gave his children.

He said: "I have benefited the most from the party’s grace in my life. Without the cultivation of the party, there would be no life course for me. " Teach your children and remember the party’s kindness all your life.

In his article Yaobang and Our Communist Youth League, he said: "Gongqing City was created by Comrade Yaobang under the guidance of the Communist Youth League. Every step of development here cannot be separated from Comrade Yaobang’s great concern. Comrade Yaobang will always be with us Communist Youth League members. Comrade Yaobang’s spirit will always reflect the Communist Youth League like the light of the sun, inspiring us to move towards a brighter tomorrow! " He led the Communist Youth League to cultivate people, which was bathed in the sunshine and dew of the party and deeply cared by Comrade Hu Yaobang, so that he could go straight against the current, cut through difficulties, make progress from scratch; Only two "perseverance" in his life (hard work and reform and innovation) can be realized, and only then can he have the "Communist Youth League Model" and "Hongdu Experience" which are famous throughout the country.

four

Jiang Zhongping’s prime of life coincides with the reform and opening-up. In the tide of the times, he made extraordinary achievements by making waves, braving the wind and waves, which is attributed to that great era. It was the great times that perfected his personality of reform and innovation, and he added luster to his times with his innocent youth.

The avenue of Jiang Zhongping’s life, the "big" ideological personality formed by the avenue, can only be alive, true and powerful if it is placed in its great era. This is the most honest ideological education he left us.

The wonderful pen and flowers published in 2014 is his last collection of paintings and calligraphy. The collection also includes the blue-and-white calligraphy giant porcelain plate "Qinyuanchun Snow" created in 2006. This large-scale porcelain calligraphy, which won the title of "the best in kiness in the world", is vigorous and forceful. Seeing this painting, his tall body, indomitable will, approachable temperament and indomitable gentleman image stood before my eyes.

Entrepreneurship, politics and art constitute his trilogy of life. Entrepreneurship and politics have enriched his artistic connotation; Wandering in art has improved his life realm. Righteousness is the cultivation and education of the party; Big is the essence of his temperament. The unity of "fairness" is the most distinctive personality of Jiang Zhongping’s life.

His eldest son, Comrade Jiang Bin, wrote in the poem "Father": "When I was a child, my father’s shoulders were the mountains that stood, and they were the lookouts." Now, standing on a high sentry post, looking into the sky, the starlight overhead, like his deep love, is clear and bright.

Outside the window, the moonlight, like water, quietly spilled on his book painting, as warm as the old days of primary school. And the looming starlight is also here at this time.

Raise your pen, and you will be in constant pain, followed by singing;

Simple and lofty sentiments, gods and virtuous,

So, you are here!

I’ve gone astray for a long time,

Looking for you in the busy crowd.

If your holy tree grows on earth,

Only on Gao Gang can it be lush and green.

Compared with pleasant tranquility,

I feel vulgar when I get along with people.

How can make-up beauty have it?

The amorous feelings of this spring stream in Yun Chuan?

Cruel passion makes infatuated people

Carve the lover’s name on the tree.

They don’t understand or don’t want to admit it.

How can lovers compete with starlight!

Lovely starlight, if I hurt you,

Please carve your own name.

The morning breeze is your kind smile,

The earth is your steady posture.

Autumn acquaintances count the years of the Communist Youth League,

The starlight of the pine moon is swaying and echoing the tide.

Singing beautifully in the starry sky,

Reflected on the vast shore of blue waves.

This place is full of vicissitudes of life,

My image flows here.

Life here, how wonderful!

A cluster of azaleas guarded the hill.

The earth here is so beautiful!

Bitian’s poems can’t hold back sorrow.

Sweet grapes on vines

Squeeze the fragrance of Joan juice from my lips.

The brightness in the shadow of Ganjiang lamp

Please wake up my dream pen, and the world will be full of baskets.

You wash the waves of the dark clouds with nail polish,

You use mountains to support the sea that holds the sun.

In your otherworldly world

Life has never been as blue as the sea;

In your burly and stalwart personality

Time is as clear as olives!

Let all creators go in and out with the times

Dreams and butterflies, a trip to the forest.

Born here with a clear spring,

Or a moss-covered stump of a fruit tree.

The clothes of the body were thrown outside,

My little soul flew into the sentry post.

Like a bird singing happily in spring,

And comb its silver wings.

Let the wings shine brightly,

Until you carry the sky and spread your wings.

A paradise that used to be poor and happy,

That’s it, shared by starlight.

Such a pure and sweet homeland,

The high starry sky stems from ardent yearning.

Stepping on the light, that shape

A stream of reeds is dyed for the beautiful spring.

Thousands of charm, feeling the power of love.

The teenagers here stand and look into the distance.

Goose,-You are my moonlight.

Sprinkle on the backbone of great love.

Skilled gardeners use branches and flowers,

How exquisite the sundial is!

The hard-working bee among the flowers,

I am also busy calculating the time skillfully.

Such a vibrant spring scenery,

How can you not share it with the world!

The proverbs of Zhuang and Lao, who have everything but nothing.

At the beginning of the universe, please settle my heart at ease.

The true meaning of Yangming studies with one mind and one mind

Let the hibiscus be clothed with stars and chardonnay, and open its heart to light.

Beautiful mountains and rivers reflect the sun and the moon,

The breeze is strong and the sea is vast.

We create and develop there.

Even though it is a dangerous beach, it is fearless of thunder storms!

Written on March 6, 2017, Peking University Wanliu Apartment.

Resume of Jiang Zhongping

Comrade Jiang Zhongping was born in January 1944 in Sunxiang Village, Tongzha Town, hanshan county City, Anhui Province. Joined the Communist Party of China (CPC) in June 1970. In September 1959, he joined the work in Nanhu Livestock Farm, Dean County, Jiangxi Province; Since September 1966, he has successively served as the workshop director and deputy director, party branch secretary and director, party branch secretary and director of down factory, deputy secretary, deputy director, secretary and director of the Party Committee of Jiangxi Gongqing Reclamation Farm; Since December 1982, he has served as member of the Standing Committee and Deputy Secretary of De ‘an County Committee of Jiangxi Province, secretary of the Party Committee and director of Gongqing Reclamation Farm of Jiangxi Province; In June 1984, he served as deputy secretary and deputy mayor of Nanchang Municipal Committee of Jiangxi Province; In April 1990, he served as deputy secretary and mayor of Nanchang Municipal Committee of Jiangxi Province; In August 1993, he served as assistant to the governor and member of the party group of Jiangxi Provincial People’s Government; In January 1998, he served as deputy governor of Jiangxi Provincial People’s Government; Since January 2003, he has served as deputy director and member of the party group of the Standing Committee of Jiangxi Provincial People’s Congress; Retired in May 2009.　

(The original title is "Associate Professor of Peking University wrote an article recalling Jiang Zhongping, the former deputy governor of Jiangxi")